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human leukemia carcinoma ccrf-cem cell line  (CEM Corporation)

 
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    CEM Corporation human leukemia carcinoma ccrf-cem cell line
    In vitro cytotoxicity of benzopyran-4-one-isoxazole conjugates (at a concentration of 25 μM) towards ( a ) human leukemia carcinoma (CCRF-CEM), ( b ) human ovarian <t>adenocarcinoma</t> (SKOV-3), ( c ) human breast tumor (MDA-MB-231), ( d ) human prostate cancer (PC-3), ( e ) androgen-independent human prostate cancer (DU-145), and ( f ) human renal carcinoma (iSLK) cell lines using DMSO and standard anticancer drug doxorubicin (Dox) (at a concentration of 5 μM) as controls after 24 and 72 h. The results are shown as the percentage of control that has no compound (set at 100%). All the experiments were performed in triplicate.
    Human Leukemia Carcinoma Ccrf Cem Cell Line, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+leukemia+carcinoma+cell+lines/ccrf+cem+cells/pmc10224329-63-7-6
    Average 90 stars, based on 1 article reviews
    human leukemia carcinoma ccrf-cem cell line - by Bioz Stars, 2026-10
    90/100 stars

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    1) Product Images from "Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds"

    Article Title: Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds

    Journal: Molecules

    doi: 10.3390/molecules28104220

    In vitro cytotoxicity of benzopyran-4-one-isoxazole conjugates (at a concentration of 25 μM) towards ( a ) human leukemia carcinoma (CCRF-CEM), ( b ) human ovarian adenocarcinoma (SKOV-3), ( c ) human breast tumor (MDA-MB-231), ( d ) human prostate cancer (PC-3), ( e ) androgen-independent human prostate cancer (DU-145), and ( f ) human renal carcinoma (iSLK) cell lines using DMSO and standard anticancer drug doxorubicin (Dox) (at a concentration of 5 μM) as controls after 24 and 72 h. The results are shown as the percentage of control that has no compound (set at 100%). All the experiments were performed in triplicate.
    Figure Legend Snippet: In vitro cytotoxicity of benzopyran-4-one-isoxazole conjugates (at a concentration of 25 μM) towards ( a ) human leukemia carcinoma (CCRF-CEM), ( b ) human ovarian adenocarcinoma (SKOV-3), ( c ) human breast tumor (MDA-MB-231), ( d ) human prostate cancer (PC-3), ( e ) androgen-independent human prostate cancer (DU-145), and ( f ) human renal carcinoma (iSLK) cell lines using DMSO and standard anticancer drug doxorubicin (Dox) (at a concentration of 5 μM) as controls after 24 and 72 h. The results are shown as the percentage of control that has no compound (set at 100%). All the experiments were performed in triplicate.

    Techniques Used: In Vitro, Concentration Assay, Control

    Related Articles

    In Vitro:

    Article Title: Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds
    Article Snippet: .. The in vitro cytotoxicity of the conjugates was evaluated using six human cancer cell lines, one human normal kidney cell line, and one mammalian normal kidney cell line, which included human leukemia carcinoma cell lines (CCRF-CEM), human ovarian adenocarcinoma cell lines (SKOV-3), human breast tumor cell lines (MDA-MB-231), human prostate cancer cell lines (PC-3), androgen-independent human prostate cancer cell lines (DU-145), human renal carcinoma (iSLK), human embryonic kidney cell lines (HEK-293), and normal mammalian kidney cell line (LLCPK) to determine the toxicity of the synthesized conjugates. .. CCRF-CEM cells were seeded at 50,000 cells in 0.1 mL per well in 96-well plates, and in the case of SKOV-3, MDA-MB-231, PC-3, DU-145, HEK-293, and LLCPK cell lines, the cells were seeded at 5000 cells in 0.1 mL per well in 96-well plates.

    Multiple Displacement Amplification:

    Article Title: Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds
    Article Snippet: .. The in vitro cytotoxicity of the conjugates was evaluated using six human cancer cell lines, one human normal kidney cell line, and one mammalian normal kidney cell line, which included human leukemia carcinoma cell lines (CCRF-CEM), human ovarian adenocarcinoma cell lines (SKOV-3), human breast tumor cell lines (MDA-MB-231), human prostate cancer cell lines (PC-3), androgen-independent human prostate cancer cell lines (DU-145), human renal carcinoma (iSLK), human embryonic kidney cell lines (HEK-293), and normal mammalian kidney cell line (LLCPK) to determine the toxicity of the synthesized conjugates. .. CCRF-CEM cells were seeded at 50,000 cells in 0.1 mL per well in 96-well plates, and in the case of SKOV-3, MDA-MB-231, PC-3, DU-145, HEK-293, and LLCPK cell lines, the cells were seeded at 5000 cells in 0.1 mL per well in 96-well plates.

    Synthesized:

    Article Title: Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds
    Article Snippet: .. The in vitro cytotoxicity of the conjugates was evaluated using six human cancer cell lines, one human normal kidney cell line, and one mammalian normal kidney cell line, which included human leukemia carcinoma cell lines (CCRF-CEM), human ovarian adenocarcinoma cell lines (SKOV-3), human breast tumor cell lines (MDA-MB-231), human prostate cancer cell lines (PC-3), androgen-independent human prostate cancer cell lines (DU-145), human renal carcinoma (iSLK), human embryonic kidney cell lines (HEK-293), and normal mammalian kidney cell line (LLCPK) to determine the toxicity of the synthesized conjugates. .. CCRF-CEM cells were seeded at 50,000 cells in 0.1 mL per well in 96-well plates, and in the case of SKOV-3, MDA-MB-231, PC-3, DU-145, HEK-293, and LLCPK cell lines, the cells were seeded at 5000 cells in 0.1 mL per well in 96-well plates.



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    In vitro cytotoxicity of benzopyran-4-one-isoxazole conjugates (at a concentration of 25 μM) towards ( a ) human leukemia carcinoma (CCRF-CEM), ( b ) human ovarian adenocarcinoma (SKOV-3), ( c ) human breast tumor (MDA-MB-231), ( d ) human prostate cancer (PC-3), ( e ) androgen-independent human prostate cancer (DU-145), and ( f ) human renal carcinoma (iSLK) cell lines using DMSO and standard anticancer drug doxorubicin (Dox) (at a concentration of 5 μM) as controls after 24 and 72 h. The results are shown as the percentage of control that has no compound (set at 100%). All the experiments were performed in triplicate.

    Journal: Molecules

    Article Title: Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds

    doi: 10.3390/molecules28104220

    Figure Lengend Snippet: In vitro cytotoxicity of benzopyran-4-one-isoxazole conjugates (at a concentration of 25 μM) towards ( a ) human leukemia carcinoma (CCRF-CEM), ( b ) human ovarian adenocarcinoma (SKOV-3), ( c ) human breast tumor (MDA-MB-231), ( d ) human prostate cancer (PC-3), ( e ) androgen-independent human prostate cancer (DU-145), and ( f ) human renal carcinoma (iSLK) cell lines using DMSO and standard anticancer drug doxorubicin (Dox) (at a concentration of 5 μM) as controls after 24 and 72 h. The results are shown as the percentage of control that has no compound (set at 100%). All the experiments were performed in triplicate.

    Article Snippet: This panel involved human leukemia carcinoma (CCRF-CEM), human ovarian adenocarcinoma (SKOV-3), human breast tumor (MDA-MB-231), human prostate cancer (PC-3), androgen-independent human prostate cancer (DU-145), and human renal carcinoma (iSLK) cell lines.

    Techniques: In Vitro, Concentration Assay, Control

    In vitro cytotoxicity of benzopyran-4-one-isoxazole conjugates (at a concentration of 25 μM) towards ( a ) human leukemia carcinoma (CCRF-CEM), ( b ) human ovarian adenocarcinoma (SKOV-3), ( c ) human breast tumor (MDA-MB-231), ( d ) human prostate cancer (PC-3), ( e ) androgen-independent human prostate cancer (DU-145), and ( f ) human renal carcinoma (iSLK) cell lines using DMSO and standard anticancer drug doxorubicin (Dox) (at a concentration of 5 μM) as controls after 24 and 72 h. The results are shown as the percentage of control that has no compound (set at 100%). All the experiments were performed in triplicate.

    Journal: Molecules

    Article Title: Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds

    doi: 10.3390/molecules28104220

    Figure Lengend Snippet: In vitro cytotoxicity of benzopyran-4-one-isoxazole conjugates (at a concentration of 25 μM) towards ( a ) human leukemia carcinoma (CCRF-CEM), ( b ) human ovarian adenocarcinoma (SKOV-3), ( c ) human breast tumor (MDA-MB-231), ( d ) human prostate cancer (PC-3), ( e ) androgen-independent human prostate cancer (DU-145), and ( f ) human renal carcinoma (iSLK) cell lines using DMSO and standard anticancer drug doxorubicin (Dox) (at a concentration of 5 μM) as controls after 24 and 72 h. The results are shown as the percentage of control that has no compound (set at 100%). All the experiments were performed in triplicate.

    Article Snippet: The in vitro cytotoxicity of the conjugates was evaluated using six human cancer cell lines, one human normal kidney cell line, and one mammalian normal kidney cell line, which included human leukemia carcinoma cell lines (CCRF-CEM), human ovarian adenocarcinoma cell lines (SKOV-3), human breast tumor cell lines (MDA-MB-231), human prostate cancer cell lines (PC-3), androgen-independent human prostate cancer cell lines (DU-145), human renal carcinoma (iSLK), human embryonic kidney cell lines (HEK-293), and normal mammalian kidney cell line (LLCPK) to determine the toxicity of the synthesized conjugates.

    Techniques: In Vitro, Concentration Assay, Control

    IC 50 (μM) of selected compounds 5a – d against human leukemia carcinoma (CCRF-CEM), human breast cancer (MDA-MB-231), human prostate cancer (PC-3), androgen-independent human prostate cancer (DU-145), and human embryonic kidney (HEK-293) cell lines.

    Journal: Molecules

    Article Title: Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds

    doi: 10.3390/molecules28104220

    Figure Lengend Snippet: IC 50 (μM) of selected compounds 5a – d against human leukemia carcinoma (CCRF-CEM), human breast cancer (MDA-MB-231), human prostate cancer (PC-3), androgen-independent human prostate cancer (DU-145), and human embryonic kidney (HEK-293) cell lines.

    Article Snippet: The in vitro cytotoxicity of the conjugates was evaluated using six human cancer cell lines, one human normal kidney cell line, and one mammalian normal kidney cell line, which included human leukemia carcinoma cell lines (CCRF-CEM), human ovarian adenocarcinoma cell lines (SKOV-3), human breast tumor cell lines (MDA-MB-231), human prostate cancer cell lines (PC-3), androgen-independent human prostate cancer cell lines (DU-145), human renal carcinoma (iSLK), human embryonic kidney cell lines (HEK-293), and normal mammalian kidney cell line (LLCPK) to determine the toxicity of the synthesized conjugates.

    Techniques: